Fig. 1. Histopathologic changes of the pancreas (H&E stain, scale bar=25 μm). (A) In normal rat, the pancreas architectures were well preserved. Islet of Langerhans (circle). AC, acinar cells; BV, blood vessels. (B) In streptozotocin (STZ) treated rat, the destruction of insulin-producing β-cells and vacuoles were observed (arrowheads). (C) In STZ+rutin treated rat, the pancreas architectures were relatively well preserved. (D) In rutin treated rat, the pancreas architectures were well preserved.

Applied Microscopy 2013;43:54-64

© 2013 Applied Microscopy