Fig. 6. Histopathologic changes of the retina (H&E stain, scale bar=50 μm). (A) In normal rat, the retina architectures were well preserved. ILM, internal limiting membrane; NFL, nerve fiber layer; GC, layer of ganglion cells; OPL, outer plexiform layer; IPL, inner plexiform layer; INL, inner nuclear layer; ONL, outer nuclear layer; R&C, layer of rod and cones; PEp, pigment epithelium; CH, choroid. (B) In streptozotocin (STZ)-treated rat, the retinal detachment (arrows) and separation of pigment epithelium and layer of optic cells were observed. (C) In STZ+rutin treated rat, the retina architectures were relatively well preserved. (D) In rutin treated rat, the retina architectures were well preserved.

Applied Microscopy 2013;43:54-64

© 2013 Applied Microscopy